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Cancer Treatment -- (AMYLOXINE®)
             Controls Metastasis

Metastasis the process by which malignant neoplasms can shed individual cells, which can travel through the lymph vessels or blood vessels, lodge in some distant organ, and grow into tumors in their own right. There are two major routes of metastasis, 1) hematogenous, in which the cells travel through the blood vessels, and 2)lymphogenous, in which the lymphatic vessels conduct the cancer cells. In the case of lymphogenous metastasis, the metastatic tumors can grow from cancers cells entrapped in the lymph nodes that collect the lymph draining from the organ where the original cancer has developed, causing the nodes to enlarge. In the case of breast cancer, the axillary (underarm) nodes are the first to become involved. In the case of cancer of the larynx (voice box), the nodes on either side of the neck (cervical nodes) are first.  Hematogenous metastases tend to deposit in the lungs, liver, and brain. Many cancers metastasize both lymphogenously and hematogenously. Most cancer operations attempt to remove not only the cancerous organ, but also the lymph nodes that drain that organ. Some types of cancer, especially the common ones (lung, breast, colon, and prostate cancers) tend to metastasize to lymph nodes first.

The first object of our study was to control Metastasis, in which cells from the tumor, seed out to other parts of the body and then grow to tumors themselves, and/or para neoplastic syndromes, in which the neoplasm secretes metabolic poisons or inappropriately large amounts of hormones that cause problems with functions of various body systems. Biological control was ruled out due to adverse side effects. Leaving chemical control as the only logical choice.  After studying numerous compounds, ozonides of terpenes hydrocarbons were studied.  Terpenes are widespread in nature, mainly in plants as constituents of essential oils. Many terpenes are hydrocarbons, but oxygen-containing compounds such as alcohols, aldehydes or ketones (terpenoids) are also found. Their building blocks is the hydrocarbon isoprene,CH2=C(CH3)-CH=CH2. Terpene hydrocarbons therefore have molecular formulas (C5H8)n, they are classified according to the number of isoprene units. The ozonized terpenes contain up to 50% oxygen by weight.

AMYLOXINE® was designed to control Metastasis, penetrate tumor cells, and inactivate the protoplasm that goes into the cells and feeds the tumor cells. If the nutritional protoplasm is eliminated, the cancer cell starves to death. AMYLOXINE® has three oxygen atoms replacing the double bonds at sites of unsaturation, creating trioxyacyclopentane. Thereby creating a highly reactive compound, the O3 as such will not be found in the red blood cell since it is not able to pass the cellular membrane. The red blood cell will react to the peroxide immediately for being a cytotoxin, and will activate its detoxification mechanism through the glutathione system. In order to keep up its system protecting the red blood cell against oxidation, the amount of glutathione consumed must be reproduced, which is done through a bypath of glycolysis, i.e. the pentose phosphate path way (PPW). The main task of the pentose phosphate pathway is to protect the hemoglobin against oxidation into methemoglobin and hence to keep up the function enabling the transmission of Oxygen. In turn, this means that the entire erythrocyte metabolism is stepped up. So that any cells of the tumor will be effectively oxidized and eliminated from the body. This is accomplished with site blocks injections, and IV drip of AMYLOXINE®.

Penetration of cell tumor was achieved with the addition of a solvent, that had no action on the tumor cell itself, but used as a vehicle, penetrating the tissues to carry AMYLOXINE® to the protoplasm thereby inactivating and therefore starved the cancer cells to death. Because of AMYLOXINE® alkaline nature, it is tumor specific to the nucleic acid of tumor cells. After prolonged IV drip AMYLOXINE® collects in the nucleus of cancer cells. Normal cells have the ability to absorb and transpose AMYLOXINE® from there nucleus.

AMYLOXINE® has been used for the past two years on breast cancer patients. With a 92% remission rate, by injection only, thereby eliminating surgery. Response to AMYLOXINE®, by other forms of cancer, are now being studied.

It took over four years to get AMYLOXINE® to clinical trials stage with as estimated cost of developing the new drug at $2.5 million to $3.8 million, excluding personnel costs. Further multi-agent randomized trials must still be conducted before the therapy will be approved by the FDA and available for general use in the United States. Chemical companies are also very interested in AMYLOXINE® for commercial applications.

LifeForce Research  is also studying other biologic sources of therapeutic agents: enzymes, proteins, and hormones which originate in animal, plants, or humans.

AMYLOXINE® is not yet available for general use in the United States. This is where we'll announce the most recent additions to our web site. If you've visited us before and want to know what's changed, take a look here first.
 
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